Association of Knee Osteoarthritis with Metabolic Syndrome in Koreans Aged 50-Years or Older
10.21215/kjfp.2019.9.2.178
- Author:
Songhwa CHOI
1
;
Min Seob SIM
;
Hyoung Gon SONG
;
Yun Mi SONG
Author Information
1. Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. yunmisong@skku.edu
- Publication Type:Original Article
- Keywords:
Osteoarthritis, knee;
Metabolic Syndrome;
Obesity;
Korea
- MeSH:
Adult;
Cholesterol;
Education;
Female;
Humans;
Knee;
Korea;
Logistic Models;
Male;
Obesity;
Obesity, Abdominal;
Osteoarthritis, Knee;
Prevalence;
Rheumatic Diseases;
Risk Factors
- From:
Korean Journal of Family Practice
2019;9(2):178-184
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Recent studies have reported the association of knee osteoarthritis (KOA) with metabolic risk factors. The objective of this study was to evaluate the association between KOA and metabolic syndrome (MetS).METHODS: The study subjects were 966 Korean adults aged ≥50 years who participated in a free-of-charge health examination provided to residents of a non-urban area. We ascertained KOA and MetS on the basis of the clinical diagnostic criteria of the American Rheumatism Association and the modified National Cholesterol Education Program's Adult Treatment Panel III, respectively. The association between KOA and MetS was evaluated using a multiple logistic regression analysis after adjusting for covariates.RESULTS: The overall prevalence rates of KOA and MetS were 34.9% and 48.7%, respectively, with higher prevalence rates in the women than in the men (P < 0.001). The risk of MetS was significantly higher in the subjects with KOA than in those without KOA (odds ratio [OR], 1.35; 95% confidence interval [CI], 1.03–1.77). Among the components of MetS, only abdominal obesity showed a significant association with KOA (OR, 1.48; 95% CI, 1.12–1.95). When the analyses were repeated to determine sex-specific relationships, the associations of KOA with MetS (P=0.069) and abdominal obesity (P=0.022) were evident in the women, but not in the men.CONCLUSION: The findings of this study suggest that women with KOA must be evaluated and managed for MetS, with special attention to abdominal obesity.
