The Relationship between Serum C-Reactive Protein and the Coffee Consumption in the Korean Adult Men and Women
10.21215/kjfp.2019.9.1.64
- Author:
Yeon Jung KIM
1
;
Keun Mi LEE
;
Seung Pil JUNG
Author Information
1. Department of Family Medicine, Yeungnam University College of Medicine, Daegu, Korea. spjung@yu.ac.kr
- Publication Type:Original Article
- Keywords:
Caffeine;
Coffee;
C-Reactive Protein;
Alcohols
- MeSH:
Adult;
Alcohols;
Antioxidants;
Beverages;
C-Reactive Protein;
Caffeine;
Cardiovascular Diseases;
Coffee;
Diabetes Mellitus, Type 2;
Female;
Humans;
Inflammation;
Korea;
Linear Models;
Male;
Nutrition Surveys;
Obesity
- From:
Korean Journal of Family Practice
2019;9(1):64-70
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Coffee is a rich source of dietary antioxidants and is one of the most popular beverages worldwide. In recent times, substantial research has been published on its anti-oxidative and anti-inflammatory effect in addition to its effect as a stimulant. Chronic low-grade inflammation is known to affect the pathogenesis of diverse diseases such as cerebrovascular and cardiovascular disease, cancer, metabolic syndrome, type 2 diabetes mellitus, and obesity. Serum C-reactive protein (CRP) is a good marker of chronic inflammation in the body. Therefore, we examined the relationship between coffee consumption and serum CRP.METHODS: Participants were 759 men and 1,003 women, aged 20–64 years, who participated in the Korea National Health and Nutrition Examination Survey, 2015. We categorized coffee consumption as follows: less than one cup a day, two to four cups a day, and five or more cups a day. Additionally, we classified women into pre- and post-menopausal women. Multiple linear regression analyses were conducted to evaluate the relationship between coffee consumption and serum CRP.RESULTS: Coffee consumption showed no measurable relationship with serum CRP in men and in pre- and post-menopausal women. However, serum CRP increased progressively with increase in coffee consumption in men reported high-risk alcohol use (P=0.005).CONCLUSION: Except for high-risk male drinkers, there is no association between coffee consumption and serum CRP.
