Clinical Significance of Bicarbonate Gap in Pediatric Patients with Acute Gastroenteritis.
- Author:
Kye Hee PARK
1
;
Seong Kwan JUNG
;
Hyung Eun YIM
;
Kee Hwan YOO
;
Young Sook HONG
;
Joo Won LEE
Author Information
1. Department of Pediatrics, College of Medicine, Korea University, Korea. czrabbit98@naver.com
- Publication Type:Comparative Study ; Original Article
- Keywords:
Acute gastroenteritis;
Metabolic acidosis;
Delta anion gap;
Delta bicarbonate
- MeSH:
Acid-Base Equilibrium;
Acidosis;
Blood Urea Nitrogen;
Creatinine;
Diarrhea;
Gastroenteritis;
Hospitalization;
Humans;
Retrospective Studies;
Sodium
- From:Journal of the Korean Society of Pediatric Nephrology
2009;13(2):235-241
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to determine the clinical value of bicarbonate gap (BG) in acute gastroenteritis by comparison of clinical manifestations and laboratory findings. METHODS: We retrospectively analyzed 135 patients who had acute gastroenteritis. We classified them into two groups: BG< or =-5 (group A), BG>-5 (group B). We made a comparative study for clinical manifestations, serum electrolyte, albumin, protein, blood urea nitrogen (BUN), creatinine, anion gap (AG), delta anion gap (deltaAG) and delta bicarbonate (deltaHCO3-) between the two groups. RESULTS: The duration of hospitalization and diarrhea was significantly longer in group A than group B. In laboratory findings, serum sodium, serum total CO2, total protein, AGcorrected and deltaAG were lower in group A than group B. deltaHCO3- and chloride were higher in group A than group B. CONCLUSION: BG may be a sensitive predictor enough to access the severity of acute gastroenteritis.
