Blood Gas Analysis of Respiratory Depression during Sevoflurane Inhalation Induction for General Anesthesia in the Disabled Patients
10.5933/JKAPD.2018.45.4.508
- Author:
Taewan YOON
1
;
Seungoh KIM
Author Information
1. Department of Pediatric Dentistry, School of Dentistry, Dankook University, Cheonan, Korea.
- Publication Type:Original Article
- Keywords:
Patient with disabilities;
Sevoflurane inhalation sedation;
General anesthesia;
Respiratory depression
- MeSH:
Anesthesia, General;
Anesthesia, Inhalation;
Anoxia;
Blood Gas Analysis;
Hemodynamics;
Humans;
Hydrogen-Ion Concentration;
Hypercapnia;
Inhalation;
Masks;
Muscle Relaxation;
Nitrous Oxide;
Oxygen;
Respiration;
Respiratory Insufficiency;
Tidal Volume;
Unconsciousness;
Veins;
Ventilation
- From:
Journal of Korean Academy of Pediatric Dentistry
2018;45(4):508-513
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Tidal volume by sevoflurane in small amounts is stable due to the increase in the breathing rate. But alveolus ventilation decreases due to sevoflurane as the degree of sedation increases; this ultimately causes PaCO2 to rise. The occurrence of suppression of breath increases the risk of severe hypoxia and hypercapnia in deeply sedated patients with disabilities. Sevoflurane inhalation anesthesia has a number of risks and may have unexpected problems with hemodynamic changes depending on the underlying state of the body. This study was conducted to examine the stability of internal acid-base system caused by respiratory depression occurring when patients with disabilities are induced by sevoflurane.Anesthetic induction was carried out by placing a mask on top of the patient's face and through voluntary breathing with 4 vol% of sevoflurane, 4 L/min of nitrous oxide, and 4 L/min of oxygen. After the patient's loss of consciousness and muscle relaxation, IV line was inserted by an expert and intravenous blood gas was analyzed by extracting blood from vein.In a deeply sedated state, the average amount of pH of the entire patients was measured as 7.36 ± 0.06. The average amount of PvCO₂ of the entire patients was measured as 48.8 ± 8.50 mmHg. The average amount of HCO₃₋ of the entire patients was measured as 27.2 ± 3.0 mmol/L.In conclusion, in dental treatment of patients with disabilities, the internal acid base response to inhalation sedation using sevoflurane is relatively stable.
