Dental Management in a Patient with Infantile Osteopetrosis : A Case Report with a 7-Year follow-up
10.5933/JKAPD.2018.45.2.257
- Author:
Minkyoung CHEON
1
;
Sunmi YANG
;
Jaehwan KIM
;
Namki CHOI
;
Seonmi KIM
Author Information
1. Department of Pediatric Dentistry, School of Dentistry, Chonnam National University, Korea. impedo@jnu.ac.kr
- Publication Type:Case Report
- Keywords:
Infantile osteopetrosis;
Oral complication;
Dental management;
Oral rehabilitation
- MeSH:
Bone Density;
Cranial Nerves;
Crowding;
Dental Care;
Dental Caries;
Denture, Partial, Removable;
Female;
Follow-Up Studies;
Humans;
Immune System;
Incisor;
Infant;
Molar;
Oral Hygiene;
Osteoclasts;
Osteomyelitis;
Osteopetrosis;
Pancytopenia;
Pediatric Dentistry;
Sepsis;
Skeleton;
Tooth;
Tooth, Deciduous;
Wound Healing
- From:
Journal of Korean Academy of Pediatric Dentistry
2018;45(2):257-263
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Osteopetrosis is characterized by impaired osteoclast function and increased bone density. Infantile osteopetrosis is a severe form of the disease and has characteristics such as diffusely sclerotic skeleton, pancytopenia, cranial nerve entrapment, infection susceptibility, and abnormal craniofacial appearance. Patients with infantile osteopetrosis often experience developmental delay, and may have a short life span.A 14-month-old girl with osteopetrosis presented to the department of pediatric dentistry. Incipient caries on deciduous incisors were observed. The patient revisited 4 years of age. Besides medical problems, oral complications such as growth retardation, narrow upper arch, crowding, dental caries, and abnormal tooth development were observed. After consultation with her pediatrician, dental treatments were performed on the deciduous molars under sedation after a prophylactic antibiotic injection. At a periodic follow-up, multiple deciduous teeth were treated and extracted, and oral-rehabilitation with a removable partial denture was initiated.Patient with osteopetrosis are highly susceptible to infection because of their compromised immune system and problems associated with wound healing that lead to osteomyelitis or sepsis development.Active participation in dental care for sugar intake management and proper oral hygiene are obligatory.
