Clinical value of the biochemical and nutritional parameters of intensive-care unit patients on mechanical ventilation.
- Author:
Seo Goo HAN
1
;
Il Woon PARK
;
Tae Woon PARK
;
Bo Kyung SHIN
;
Dong Seok MOON
;
Hyeong Jin KIM
;
Jae Ho CHUNG
;
Jung Eun CHOI
;
Young Jun WON
Author Information
1. Department of Internal Medicine, Myongji Hospital, Kwandong University College of Medicine, Goyang, Korea. yjwon@kd.ac.kr
- Publication Type:Original Article
- Keywords:
Nutrition assessment;
Mechanical ventilation;
Malnutrition;
Mnemia
- MeSH:
Anemia;
Blood Urea Nitrogen;
Calcium;
Cholesterol;
Creatinine;
Hematocrit;
Hospitalization;
Humans;
Length of Stay;
Lymphocytes;
Malnutrition;
Nutrition Assessment;
Nutritional Status;
Phosphorus;
Prevalence;
Regression Analysis;
Respiration, Artificial*;
Retrospective Studies
- From:Korean Journal of Medicine
2007;73(2):151-158
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The nutritional status of critical-ill patients is important for recovering from the disease itself. Therefore, this present study was designed to assess the biochemical and nutritional parameters of Intensive-Care Unit (ICU) patients on mechanical ventilation. METHODS: We retrospectively reviewed the medicial records of 126 patients (male/female=72/54) who were on mechanical ventilationin the ICU. The nutritional parameters such as serum total protein, albumin, hemoglobin, hematocrit, calcium, phosphorus, total cholesterol, % lymphocytes, blood urea nitrogen (BUN), and creatinine (Cr) were measured at the beginning of mechanical ventilation. We also measured the outcome variables such as the duration of mechanical ventilation, the ICU length of stay and the hospitalization period. We analyzed the relationship between the nutritional parameters and the outcome variables of ICU patients on mechanical ventilation. RESULTS: The level of hemoglobin was negatively correlated with the outcome variables; the ICU length of stay (p<0.05), the hospitalized period (p<0.01), and the duration of mechanical ventilation (p<0.01). The creatinine level was positively correlated with the outcome variables; the ICU length of stay (p<0.01), the hospitalized period (p<0.01) and the duration of mechanical ventilation (p<0.05). On the multiple regression analysis, the serum total protein, albumin, calcium, inorganic phosphorus, BUN and creatinine were independent factors affecting the duration of mechanical ventilation. CONCLUSIONS: These findings indicate that ICU patients with mechanical ventilation have a risk for malnutrition and anemia. So, an adequate nutritional intervention is required for these patients in order to decrease the prevalence of malnutrition and anemia.
