Non-celiac Gluten Sensitivity
- Author:
Ra Ri CHA
1
;
Hyun Jin KIM
Author Information
- Publication Type:Review
- Keywords: Nonceliac gluten sensitivity; Functional gastrointestinal disorders; Abdominal pain; Diarrhea; Glutens
- MeSH: Abdominal Pain; Biomarkers; Celiac Disease; Diarrhea; Diet; Diet, Gluten-Free; Eating; Gastrointestinal Diseases; Gastrointestinal Tract; Glutens; Humans; Irritable Bowel Syndrome; Nervous System; Wheat Hypersensitivity
- From:The Korean Journal of Gastroenterology 2020;75(1):11-16
- CountryRepublic of Korea
- Language:Korean
- Abstract: Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. Gluten-related disorder groups are manifested by symptoms of gastrointestinal tract disorders, as well as hematological dermatological endocrinological, gynecological, rheumatological and nervous system symptoms. It is believed that NCGS represents heterogeneous groups with different subgroups characterized by different etiologies, clinical histories and clinical courses. There also appears to be an overlap between NCGS and irritable bowel syndrome (IBS). There is a need for establishing strict criteria for diagnosing NCGS. The absence of validated biomarkers remains a significant limitation for research studies on NCGS. New evidence shows that a gluten-free diet may be beneficial for some patients with gastrointestinal symptoms, such as those symptoms commonly found in patients with IBS. Further studies about NCGS are needed.
