Negative myoclonus associated with pregabalin
10.12701/yujm.2018.35.2.240
- Author:
Kwan Do PARK
1
;
Min Ku KIM
;
Se Jin LEE
Author Information
1. Department of Neurology, Yeungnam University College of Medicine, Daegu, Korea. sejinmayo@ynu.ac.kr
- Publication Type:Case Report
- Keywords:
Myoclonus;
Negative myoclonus;
Pregabalin
- MeSH:
Aged, 80 and over;
Dyskinesias;
Humans;
Lorazepam;
Muscle Contraction;
Myoclonus;
Neuralgia;
Pregabalin;
Seizures
- From:Yeungnam University Journal of Medicine
2018;35(2):240-243
- CountryRepublic of Korea
- Language:English
-
Abstract:
Negative myoclonus (NM) is a jerky, shock-like involuntary movement caused by a sudden, brief interruption of muscle contraction. An 80-year-old man presented with multifocal NM and confusion. Two days before the onset of NM, he commenced the intake of pregabalin at a dose of 150 mg/day for neuropathic pain. His NM resolved completely and mental status improved gradually after the administration of lorazepam intravenously and the discontinuation of pregabalin. Our study suggests that pregabalin can cause NM even in patients without a history of seizures.
