Ankylosing spondylitis associated with balanced reciprocal X-1 translocation
10.12701/yujm.2017.34.1.80
- Author:
Young Hoon KIM
1
;
Jung Ouk LEE
Author Information
1. Department of Internal Medicine, Busan St. Mary's Hospital, Busan, Korea. cocoabing@gmail.com
- Publication Type:Case Report
- Keywords:
Ankylosing spondylitis;
Genetic translocation;
Hypogonadism
- MeSH:
Adult;
Buttocks;
Female;
Humans;
Hypogonadism;
Joints;
Magnetic Resonance Imaging;
Ovary;
Spondylitis, Ankylosing;
Translocation, Genetic;
Uterus
- From:Yeungnam University Journal of Medicine
2017;34(1):80-83
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A number of research papers have reported more frequent occurrence of rheumatic/autoimmune disease among patients with hypogonadism or a chromosomal anomaly with potential X-chromosome defects. A 30-year-old female patient came to the hospital with a main cause of bilateral buttock pain, which began two years ago and worsened seven days ago. Ankylosing spondylitis with invasion of both sacral-iliac joints was observed. On magnetic resonance imaging, although the uterus was observed normally, an ovary was not observed. In a chromosome test, balanced reciprocal X-1 translocation of 46,X,t(X;1)(p10;q10) was diagnosed. Here, we report on the first case involving ankylosing spondylitis accompanied by balanced reciprocal X-1 translocation.
