Rheumatoid arthritis accompanied by Gitelman syndrome
10.12701/yujm.2017.34.1.101
- Author:
Min Gi PARK
1
;
Ji Hyun LEE
;
Sung Jun KIM
;
Su Ho PARK
;
Suk Ki PARK
;
Joon Sul CHOI
;
Ji Yeon HWANG
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, Korea. ete@lycos.co.kr
- Publication Type:Case Report
- Keywords:
Gitelman syndrome;
Rheumatoid arthritis;
Furosemide;
Thiazides;
Genetic testing
- MeSH:
Adult;
Alkalosis;
Arthritis, Rheumatoid;
Fatigue;
Furosemide;
Genetic Testing;
Gitelman Syndrome;
Hand;
Humans;
Hypesthesia;
Hypokalemia;
Muscle Cramp;
Paralysis;
Solute Carrier Family 12, Member 3;
Thiazides;
Tremor
- From:Yeungnam University Journal of Medicine
2017;34(1):101-105
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gitelman syndrome is a condition caused by a mutation of the thiazide sensitive Na-Cl cotransporter gene on the distal convoluted tubule. It results in a variety of clinical features, including hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. It is often diagnosed in asymptomatic adults presented with unexplained hypokalemia; however, it is sometimes associated with muscular cramps, numbness, fatigue, weakness, or paralysis. We experienced a case of rheumatoid arthritis accompanied by Gitelman syndrome, presented with hand tremor. We diagnosed her using renal clearance study and genetic analysis. Here, we report our experiences regarding this case along with a literature review.
