Severe chest pain with mid-ventricular obstruction in a patient with hyperthyroidism
10.12701/yujm.2017.34.1.128
- Author:
Jong Ho NAM
1
;
Jang Won SON
;
Geu Ru HONG
Author Information
1. Cardiology Division, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Hyperthyroidism;
Coronary artery disease;
Ventricular function
- MeSH:
Blood Pressure;
Cardiomyopathy, Hypertrophic;
Chest Pain;
Coronary Angiography;
Coronary Artery Disease;
Echocardiography;
Female;
Humans;
Hypertension;
Hyperthyroidism;
Methimazole;
Middle Aged;
Oxygen;
Peripheral Arterial Disease;
Stroke;
Thorax;
Ventricular Function
- From:Yeungnam University Journal of Medicine
2017;34(1):128-131
- CountryRepublic of Korea
- Language:English
-
Abstract:
Mid-ventricular obstruction (MVO) rarely occurs in patients without hypertrophic cardiomyopathy. Increased cardiac contractility may play an important role in causing MVO. We experienced a case of severe chest pain and MVO in a 50-year-old female patient. She had hypertension, diabetes, stroke and peripheral artery disease. Her blood pressure was very high (222/122 mmHg) with severe fluctuation. The transthoracic echocardiography revealed MVO accompanied by hyper-dynamic left ventricular systolic function. We regarded her chest pain and MVO as secondary findings related to other diseases. Coronary angiography and several tests for uncontrolled hypertension were performed, and those evaluations revealed that she had coronary artery disease and hyperthyroidism. We considered that the increase in the myocardial oxygen demand in response to the increase in cardiac contractility and workload associated with hyperthyroidism aggravated her symptoms and MVO. She was treated with methimazole and beta blockers and her symptoms dramatically improved.
