Systemic Lupus Erythematosus Associated Pitfalls on ¹⁸F-FDG PET/CT: Reactive Follicular Hyperplasia, Kikuchi-Fujimoto Disease, Inflammation and Lymphoid Hyperplasia of the Spleen Mimicking Lymphoma
10.1007/s13139-017-0471-z
- Author:
William MAKIS
1
;
Anthony CIARALLO
;
Gonzalez Verdecia MILENE
;
Stephan PROBST
Author Information
1. Department of Diagnostic Imaging, CCI, 11560 University AveNW, Edmonton, AB T6G 1Z2, Canada. makisw79@yahoo.com
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
SLE;
Lymphoma;
Kikuchi-Fujimoto disease;
Spleen;
PET/CT
- MeSH:
Brain;
Electrons;
Histiocytic Necrotizing Lymphadenitis;
Humans;
Hyperplasia;
Inflammation;
Kidney;
Lupus Erythematosus, Systemic;
Lymph Nodes;
Lymphoma;
Positron-Emission Tomography and Computed Tomography;
Spleen
- From:Nuclear Medicine and Molecular Imaging
2018;52(1):74-79
- CountryRepublic of Korea
- Language:English
-
Abstract:
Systemic lupus erythematosus (SLE) is associated with a variety of inflammatory processes that can affect the lymph nodes, brain, kidneys, and spleen. We present two patients with SLE in whom SLE-associated conditions complicated interpretation of ¹⁸F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging of the lymph nodes and the spleen. The imaging findings mimicked lymphoma, but histopathological evaluation showed benign processes including reactive follicular hyperplasia in the lymph nodes, Kikuchi-Fujimoto disease in perisplenic lymph nodes, and inflammatory changes and lymphoid hyperplasia in the spleen.
