⁶⁸Gallium-Arginine-Glycine-Aspartic Acid and ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Chondroblastic Osteosarcoma of the Skull
10.1007/s13139-016-0400-6
- Author:
Akintunde ORUNMUYI
1
;
Moshe MODISELLE
;
Thabo LENGANA
;
Thomas EBENHAN
;
Mariza VORSTER
;
Mike SATHEKGE
Author Information
1. Department of Nuclear Medicine, University of Pretoria and Steve Biko Academic Hospital, Private Bag X169, Pretoria 0001, South Africa. mike.sathekge@up.ac.za, akin2nde@gmail.com, modisellemoshe@yahoo.co.uk, tlengana@gmail.com, thomas.ebenhan@gmail.com, marizavorster@gmail.com
- Publication Type:Case Report
- Keywords:
Chondroblastic Osteosarcoma;
¹⁸F-FDG;
⁶⁸Ga-RGD;
PET/CT
- MeSH:
Chondrocytes;
Electrons;
Humans;
Male;
Osteosarcoma;
Positron-Emission Tomography and Computed Tomography;
Skull
- From:Nuclear Medicine and Molecular Imaging
2017;51(3):271-273
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report the case of a 32 year-old male with Chondroblastic Osteosarcoma of the skull, which was imaged with both ¹⁸[F]fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) and ⁶⁸Gallium-arginine-glycine-aspartic acid (⁶⁸Ga-RGD) PET/CT. The ¹⁸F-FDG PET/CT did not demonstrate the tumour,whereas the ⁶⁸Ga-RGD PET/CT clearly depicted a left-sided frontal tumour. ⁶⁸Ga-RGD PET/CT may be a clinically useful imaging modality for early detection of recurrent osteosarcoma, considering the limitations of ¹⁸F-FDG PET in a setting of low glycolytic activity.