Analysis of Risk Factors for Postoperative Morbidity in Perforated Peptic Ulcer.
- Author:
Jae Myung KIM
1
;
Sang Ho JEONG
;
Young Joon LEE
;
Soon Tae PARK
;
Sang Kyung CHOI
;
Soon Chan HONG
;
Eun Jung JUNG
;
Young Tae JU
;
Chi Young JEONG
;
Woo Song HA
Author Information
- Publication Type:Original Article
- Keywords: Peptic ulcer; Peptic ulcer perforation; Septic shock; Health status index
- MeSH: Diabetes Mellitus; Emergencies; Health Status Indicators; Humans; Hypertension; Incidence; Lung Diseases; Multivariate Analysis; Peptic Ulcer; Peptic Ulcer Perforation; Postoperative Complications; Risk Factors; Shock; Shock, Septic
- From:Journal of Gastric Cancer 2012;12(1):26-35
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: Emergency operations for perforated peptic ulcer are associated with a high incidence of postoperative complications. While several studies have investigated the impact of perioperative risk factors and underlying diseases on the postoperative morbidity after abdominal surgery, only a few have analyzed their role in perforated peptic ulcer disease. The purpose of this study was to determine any possible associations between postoperative morbidity and comorbid disease or perioperative risk factors in perforated peptic ulcer. MATERIALS AND METHODS: In total, 142 consecutive patients, who underwent surgery for perforated peptic ulcer, at a single institution, between January 2005 and October 2010 were included in this study. The clinical data concerning the patient characteristics, operative methods, and complications were collected retrospectively. RESULTS: The postoperative morbidity rate associated with perforated peptic ulcer operations was 36.6% (52/142). Univariate analysis revealed that a long operating time, the open surgical method, age (> or =60), sex (female), high American Society of Anesthesiologists (ASA) score and presence of preoperative shock were significant perioperative risk factors for postoperative morbidity. Significant comorbid risk factors included hypertension, diabetes mellitus and pulmonary disease. Multivariate analysis revealed a long operating time, the open surgical method, high ASA score and the presence of preoperative shock were all independent risk factors for the postoperative morbidity in perforated peptic ulcer. CONCLUSIONS: A high ASA score, preoperative shock, open surgery and long operating time of more than 150 minutes are high risk factors for morbidity. However, there is no association between postoperative morbidity and comorbid disease in patients with a perforated peptic ulcer.
