Korean Medication Algorithm for Bipolar Disorder 2018: Overview
- Author:
Won KIM
1
;
Won Myong BAHK
;
Bo Hyun YOON
;
Duk In JON
;
Jeong Seok SEO
;
Jung Goo LEE
;
Young Sup WOO
;
Jong Hyun JEONG
;
Moon Doo KIM
;
InKi SOHN
;
Se Hoon SHIM
;
Hoo Rim SONG
;
Kyung Joon MIN
Author Information
1. Department of Psychiatry, Seoul Paik Hospital, College of Medicine, Inje University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Bipolar disorder;
KMAP-BP 2018, Pharmacotherapy;
Algorithm
- MeSH:
Advisory Committees;
Antipsychotic Agents;
Bipolar Disorder;
Consensus;
Depression;
Hearing;
Hope;
Humans
- From:
Mood and Emotion
2018;16(1):1-12
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The Korean Medication Algorithm for Bipolar Disorder (KMAP-BP), which was first published in 2002 and updated in 2006, 2010 and 2014, is revised again through the expert's consensus of opinion.METHODS: Out of eighty-four member of the review committee, sixty-one members completed the survey. We analyzed the answers, and thus discussed the data and held a clinician hearing on the results. Therefore, we report the results of KMAP-BP 2018.RESULTS: The preferred first-step strategies for acute euphoric mania are the combination of mood stabilizer (MS) and atypical antipsychotics (AAP), MS monotherapy and AAP monotherapy. For psychotic mania, combination of MS and AAP, and AAP monotherapy are preferred. The first-step strategies for acute bipolar, mild to moderate, depression are MS monotherapy, lamotrigine (LTG) monotherapy, AAP monotherapy, MS+AAP combination, AAP+LTG combination and MS+LTG combination. For non-psychotic severe depression, the MS+AAP combination, AAP+LTG combination and MS+LTG combination are preferred. For psychotic severe depression, the MS+AAP, AAP+antidepressant (AD) and AAP+LTG are preferred.CONCLUSION: We surveyed the expert consensus for the treatment of bipolar disorders and developed KMAP-BP 2018. We hope that this KMAP-BP 2018 is going to be helpful for clinicians to treat the patients with bipolar disorder.
