Relationship between Suicidal Ideation and Plasma C-Reactive Protein Level in General Population : The Korean National Health and Nutrition Examination Survey
- Author:
Jung An LEE
1
;
Seon Cheol PARK
;
Gyung Mee KIM
;
Bong Ju LEE
;
Sung Woo PARK
;
Mi Kyoung SEO
;
Jung Goo LEE
Author Information
1. Department of Psychiatry, Ceollege of Medicine, Haeundae Paik Hospital, Inje University, Busan, Korea. iybihwc@naver.com
- Publication Type:Original Article
- Keywords:
C-reactive protein (CRP);
Decision tree;
General population;
Plasma;
Suicidal ideation
- MeSH:
C-Reactive Protein;
Decision Trees;
Humans;
Nutrition Surveys;
Plasma;
Research Subjects;
Suicidal Ideation
- From:
Mood and Emotion
2018;16(1):38-43
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The purpose of this study is to inquire into the relationship between the association of suicidal ideation and the plasma C-reactive protein level in the general population.METHODS: This study selected a total of 5,090 subjects who have responded to the survey item on suicidal ideation status, and received the plasma C-reactive protein test, as a research subject using the 2015 data of the National Health and Nutrition Survey. This study conducted a covariance analysis by correcting a potential influence of demographic and hematological factors. Besides, this study intended to define the cut-off value of the optimum plasma C-reactive protein level, which once identified can distinguish between a subject with and without suicidal ideation using the model of the decision tree.RESULTS: The Plasma C-reactive protein level of a subject having suicidal ideation was noted as being significantly higher than the one having no suicidal ideation in the covariance analysis (p=0.046). In addition, the proper cut-off value of the plasma C-reactive protein level between the subjects with and without suicidal ideation was found to be 1.30 mg/L (p=0.003).CONCLUSION: It is noted that the high plasma C-reactive protein level showed a significant correlation with individuals with noted suicidal ideation. In addition, this study has significance in that it presented that the plasma C-reactive protein concentration has the possibility as an accurate and significant marker of suicidal ideation in the general population.
