Effects of 12 Weeks of Combined Exercise on Vascular Function-Related Inflammation Factors, Carotid Intima-Media Thickness and Physical Fitness in Obese 40s-Aged Women with Metabolic Syndrome
10.5763/kjsm.2019.37.4.184
- Author:
Kijin KIM
1
Author Information
1. Department of Physical Education, College of Physical Education, Keimyung University, Daegu, Korea. Kjk744@kmu.ac.kr
- Publication Type:Original Article
- Keywords:
Exercise;
Intima-media thickness;
Metabolic syndrome;
Woman
- MeSH:
Blood Glucose;
Blood Pressure;
Body Composition;
Body Weight;
Carotid Arteries;
Carotid Intima-Media Thickness;
Exercise;
Female;
Glucose;
Hand Strength;
Humans;
Inflammation;
Interleukin-6;
Leptin;
Metabolism;
Necrosis;
Physical Fitness;
Triglycerides
- From:The Korean Journal of Sports Medicine
2019;37(4):184-194
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to investigate the effects of 12 weeks of combined exercise on vascular function-related inflammation, carotid intima-media thickness and fitness factors in obese middle-aged women with metabolic syndrome.METHODS: The subjects of this study were 40 middle-aged women in their 40s with metabolic syndrome but no specific disease. The exercise group performed aerobic exercise and resistance exercise five times a week for 12 weeks, and then measured body composition, blood pressure, vascular function-related inflammation factors, metabolic syndrome factors, carotid intima-media thickness, and physical factors.RESULTS: The exercise group showed a significant (p<0.05) reduction after exercise in all items related to body composition, systolic and diastolic blood pressure, and intima-media thickness of the right carotid and left carotid arteries. Exercise group showed a significant decrease (p<0.05) after exercise in interleukin-6, tumor necrosis factor-α, leptin, and all items of glucose metabolism-related variables. The exercise group showed a significant (p<0.05) increase after exercise physical efficiency index, grip strength, sit-ups, and sit & reach. After 12 weeks of exercise training, the reduction of intima-media thickness of the carotid artery was significantly (p<0.05) correlated with the improvement of body weight, systolic and diastolic blood pressure, grip and sit & reach, blood HbA1c, and triglyceride concentration.CONCLUSION: In conclusion, metabolic syndrome improved the body composition, blood glucose metabolism and lipid variables after 12 weeks of combined exercise program for obese middle-aged women. Significant improvement in blood pressure and carotid endometrial thickness, which is a function-related indicator, was confirmed.
