Similarities of Aspects of Biological Rhythms between Major Depression and Bipolar II Disorder Compared to Bipolar I Disorder: A Finding from the Early-Onset Mood Disorder Cohort
- Author:
Su Cheol KIM
1
;
Chul Hyun CHO
;
Yujin LEE
;
Ju Yeon SEO
;
Yong Min AHN
;
Se Joo KIM
;
Tae Hyon HA
;
Boseok CHA
;
Eunsoo MOON
;
Dong Yeon PARK
;
Ji Hyun BAEK
;
Hee Ju KANG
;
Hyonggin AN
;
Heon Jeong LEE
Author Information
- Publication Type:Original Article
- Keywords: Biological rhythm; Bipolar disorder; Major depressive disorder; Cohort
- MeSH: Bipolar Disorder; Cohort Studies; Depression; Depressive Disorder, Major; Korea; Mood Disorders; Neuropsychiatry; Periodicity
- From:Psychiatry Investigation 2019;16(11):829-835
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The biological rhythm is closely related to mood symptoms. The purpose of this study was to assess the differences in biological rhythms among subjects with mood disorder [bipolar I disorder (BD I), bipolar II disorder (BD II), major depressive disorder (MDD)] and healthy control subjects.METHODS: A total of 462 early-onset mood disorder subjects were recruited from nine hospitals. The controls subjects were recruited from the general population of South Korea. Subject groups and control subject were evaluated for the Korean language version of Biological Rhythms Interview of Assessment in Neuropsychiatry (K-BRIAN) at the initial evaluation.RESULTS: The mean K-BRIAN scores were 35.59 [standard deviation (SD)=13.37] for BD I, 43.05 (SD=11.85) for BD II, 43.55 (SD=12.22) for MDD, and 29.1 (SD=8.15) for the control group. In the case of mood disorders, biological rhythm disturbances were greater than that in the control group (p<0.05). A significant difference existed between BD I and BD II (BD I
