68Ga-PSMA: a One-stop Shop in Radioactive Iodine Refractory Thyroid Cancer?
10.1007/s13139-019-00621-x
- Author:
Thabo LENGANA
1
;
Ismaheel O LAWAL
;
Kgomotso MOKOALA
;
Mariza VORSTER
;
Mike M SATHEKGE
Author Information
1. Department of Nuclear Medicine, University of Pretoria & Steve Biko Academic Hospital, Private Bag X169, Pretoria 0001, South Africa. mike.sathekge@up.ac.za
- Publication Type:Case Report
- Keywords:
⁶⁸Ga-PSMA;
¹⁸F-FDG;
Thyroid cancer;
Radioactive iodine refractory thyroid
- MeSH:
Female;
Follow-Up Studies;
Humans;
Iodine;
Middle Aged;
Positron-Emission Tomography and Computed Tomography;
Thyroglobulin;
Thyroid Gland;
Thyroid Neoplasms;
Thyroidectomy
- From:Nuclear Medicine and Molecular Imaging
2019;53(6):442-445
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case of a 47-year-old female known with metastatic papillary thyroid cancer. Her treatment history included total thyroidectomy and 3 previous radio ablations with a cumulative dose of 950 mCi of ¹³¹I. On follow-up, her thyroglobulin levels had demonstrated a rising trend (from 3789.0 to 4240.0 ug/L) despite a ¹²³I whole-body scan demonstrating a reduction in tracer avid lesions. She was suspected of having radio-resistant disease. The patient underwent both ¹⁸F-FDG and ⁶⁸Ga-PSMA PET/CT imaging with both scans demonstrating congruent lesions however with far greater intensity on the ⁶⁸Ga-PSMA study.
