Successful Treatment of Neonatal Herpes Simplex Infection Presenting as Fulminant Hepatitis with Acyclovir and Peritoneal Dialysis
- Author:
Seonghye CHOI
1
;
Jang Hoon LEE
;
Moon Sung PARK
Author Information
- Publication Type:Case Report
- Keywords: Infant, newborn; Fulminant hepatitis; Liver failure; Herpes simplex
- MeSH: Acyclovir; Hepatitis; Herpes Simplex; Humans; Infant, Newborn; Korea; Liver Failure; Liver Failure, Acute; Liver Transplantation; Mortality; Peritoneal Dialysis; Renal Insufficiency; Simplexvirus
- From:Neonatal Medicine 2019;26(4):229-232
- CountryRepublic of Korea
- Language:Korean
- Abstract: Disseminated neonatal herpes simplex virus (HSV) infection is a severe disease with a high mortality rate. Here, we report the patient presented with fulminant hepatic failure secondary to HSV infection followed by renal failure without any mucocutaneous symptoms. The patient recovered after treatment with acyclovir and peritoneal dialysis. This is the first known case of a patient in Korea who survived disseminated HSV infection with fulminant liver failure followed by renal failure without undergoing liver transplantation.