The Relationship between Pulmonary Function and Serum Uric Acid Level in the Korean Population
10.15384/kjhp.2019.19.4.196
- Author:
Gi Tae KIM
1
;
Jae Woong SULL
Author Information
1. Department of Senior Healthcare, General Graduate School, Eulji University, Seongnam, Korea.
- Publication Type:Original Article
- Keywords:
Uric acid;
Lung diseases;
Hyperuricemia;
Vital capacity;
Forced expiratory volume
- MeSH:
Adult;
Cardiovascular Diseases;
Cohort Studies;
Female;
Forced Expiratory Volume;
Gout;
Humans;
Hyperuricemia;
Korea;
Lung;
Lung Diseases;
Male;
Nutrition Surveys;
Prospective Studies;
Spirometry;
Uric Acid;
Vital Capacity
- From:Korean Journal of Health Promotion
2019;19(4):196-201
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Forced vital capacity (FVC), forced expiratory volume in the first second (FEV₁), and the ratio of FEV₁ to FVC (FEV₁/FVC) are considered as the major spirometry parameters. Serum uric acid is associated with increased risk of gout and cardiovascular disease. We analyzed the relationship between pulmonary function and serum uric acid level in the Korean men and women.METHODS: This study was based on the data collected during the 2016 Korea National Health and Nutrition Examination Survey (KNHANES VII-1). A total of 3,411 adults were retrieved from KNHANES VII-1. Among 3,411 adults, 1,500 were men and 1,911 were women.RESULTS: In this study, a significant negative correlation was observed between serum uric acid level and pulmonary function values only in females. Also, in the male non-smoker group, pulmonary function values were negatively associated with serum uric acid level (FVC %predicted, β=−0.014; FEV₁ %predicted, β=−0.015).CONCLUSIONS: In this study, hyperuricemia was associated with the low lung function in males and females. In order to obtain an accurate assessment of the association between hyperuricemia and pulmonary function values, further prospective cohort study in the future is necessary.
