Severe Hyperhidrosis in Apert Syndrome: A Case Report
- Author:
Hanjae LEE
1
;
Sungjun CHOI
;
Ji Hoon YANG
;
Jungyoon MOON
;
Dae Hun SUH
Author Information
1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. daehun@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Apert syndrome;
Hyperhidrosis
- MeSH:
Acne Vulgaris;
Acrocephalosyndactylia;
Craniosynostoses;
Dermatology;
Female;
Foot;
Hand;
Humans;
Hyperhidrosis;
Infant;
Parturition;
Skull;
Sweat;
Sweating;
Syndactyly
- From:Korean Journal of Dermatology
2019;57(9):548-550
- CountryRepublic of Korea
- Language:English
-
Abstract:
Apert syndrome is a rare genetic disorder characterized by malformations of the skull, face, hands, and feet. We report a case of severe hyperhidrosis in a 13-month-old female infant with Apert syndrome who was born with craniosynostosis, midface hypoplasia, and syndactyly of both hands. She had a history of excessive sweating since birth and this was confirmed using the iodine-starch test. Hyperhidrosis was first reported as a key cutaneous manifestation of Apert syndrome in 1993. However, the main focus in the field of dermatology is on antibiotic-refractory acne, which serves as another cutaneous hallmark of the disease. This is the first report in the Korean literature that describes hyperhidrosis in Apert syndrome. We highlight the presentation of hyperhidrosis as a key cutaneous manifestation in Apert syndrome.
