Computer programme to assess mandibular cortex morphology in cases of medication-related osteonecrosis of the jaw with osteoporosis or bone metastases
10.5624/isd.2019.49.4.281
- Author:
Ichiro OGURA
1
;
Eizaburo KOBAYASHI
;
Ken NAKAHARA
;
Maiko HAGA-TSUJIMURA
;
Kensuke IGARASHI
;
Akitoshi KATSUMATA
Author Information
1. Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan. ogura@ngt.ndu.ac.jp
- Publication Type:Original Article
- Keywords:
Image Processing, Computer-Assisted;
Radiography, Panoramic;
Bisphosphonate-Associated Osteonecrosis of the Jaw;
Osteoporosis
- MeSH:
Bisphosphonate-Associated Osteonecrosis of the Jaw;
Classification;
Cytochrome P-450 CYP1A1;
Evaluation Studies as Topic;
Humans;
Image Processing, Computer-Assisted;
Jaw;
Neoplasm Metastasis;
Osteonecrosis;
Osteoporosis;
Radiography, Panoramic
- From:Imaging Science in Dentistry
2019;49(4):281-286
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The purpose of this study was to evaluate the morphology of the mandibular cortex in cases of medication-related osteonecrosis of the jaw (MRONJ) in patients with osteoporosis or bone metastases using a computer programme.MATERIALS AND METHODS: Fifty-four patients with MRONJ (35 with osteoporosis and 19 with bone metastases) were examined using panoramic radiography. The morphology of the mandibular cortex was evaluated using a computer programme that scanned the mandibular inferior cortex and automatically assessed the mandibular cortical index (MCI) according to the thickness and roughness of the mandibular cortex, as follows: normal (class 1), mildly to moderately eroded (class 2), or severely eroded (class 3). The MCI classifications of MRONJ patients with osteoporosis or bone metastases were evaluated with the Pearson chi-square test. In these analyses, a 5% significance level was used.RESULTS: The MCI of MRONJ patients with osteoporosis (class 1: 6, class 2: 15, class 3: 14) tended to be higher than that of patients with bone metastases (class 1: 14, class 2: 5, class 3: 0) (P=0.000).CONCLUSION: The use of a computer programme to assess mandibular cortex morphology may be an effective technique for the objective and quantitative evaluation of the MCI in MRONJ patients with osteoporosis or bone metastases.
