The extension of the largest generalized-eigenvalue based distance metric D(ij)(γ₁) in arbitrary feature spaces to classify composite data points
- Author:
Mosaab DAOUD
1
Author Information
- Publication Type:Original Article
- Keywords: classification; clustering; composite data points; limiting dispersion map; linear (non-linear) transformation function; sets of sequences; statistical learning
- MeSH: Classification; Cluster Analysis; Data Mining; Dataset; Machine Learning; Multivariate Analysis
- From:Genomics & Informatics 2019;17(4):39-
- CountryRepublic of Korea
- Language:English
- Abstract: Analyzing patterns in data points embedded in linear and non-linear feature spaces is considered as one of the common research problems among different research areas, for example: data mining, machine learning, pattern recognition, and multivariate analysis. In this paper, data points are heterogeneous sets of biosequences (composite data points). A composite data point is a set of ordinary data points (e.g., set of feature vectors). We theoretically extend the derivation of the largest generalized eigenvalue-based distance metric D(ij)(γ₁) in any linear and non-linear feature spaces. We prove that D(ij)(γ₁) is a metric under any linear and non-linear feature transformation function. We show the sufficiency and efficiency of using the decision rule δ(Ξi) (i.e., mean of D(ij)(γ₁)) in classification of heterogeneous sets of biosequences compared with the decision rules min(Ξi) and median(Ξi). We analyze the impact of linear and non-linear transformation functions on classifying/clustering collections of heterogeneous sets of biosequences. The impact of the length of a sequence in a heterogeneous sequence-set generated by simulation on the classification and clustering results in linear and non-linear feature spaces is empirically shown in this paper. We propose a new concept: the limiting dispersion map of the existing clusters in heterogeneous sets of biosequences embedded in linear and nonlinear feature spaces, which is based on the limiting distribution of nucleotide compositions estimated from real data sets. Finally, the empirical conclusions and the scientific evidences are deduced from the experiments to support the theoretical side stated in this paper.
