Effect of Repetitive Transcranial Magnetic Stimulation in Post-stroke Patients with Severe Upper-Limb Motor Impairment
- Author:
Ju Sun KIM
1
;
Dae Hyun KIM
;
Hyun Jung KIM
;
Kang Jae JUNG
;
Juntaek HONG
;
Deog Young KIM
Author Information
- Publication Type:Original Article
- Keywords: Transcranial magnetic stimulation; Recovery of function; Upper extremity; Cortical excitability
- MeSH: Cerebral Cortex; Evoked Potentials, Motor; Hand; Humans; Recovery of Function; Shoulder; Transcranial Magnetic Stimulation; Upper Extremity; Wrist
- From:Brain & Neurorehabilitation 2020;13(1):3-
- CountryRepublic of Korea
- Language:English
- Abstract: Repetitive transcranial magnetic stimulation (rTMS) has been known to improve the motor function through modulation of excitability in the cerebral cortex. However, most studies with rTMS were limited to post-stroke patients with mild to moderate motor impairments. The effect of rTMS on severe upper-limb motor impairment remains unclear. Therefore, this study investigated the effects of rTMS on the upper extremity function in post-stroke patients with severe upper-limb motor impairment. Subjects were divided into 3 groups, low-, high-frequency rTMS and control group were received stimulation 10 times for 2 weeks. The motor scale of Fugl-Meyer Assessment (FMA) and cortical excitability on the unaffected hemisphere were measured before and after performing 10 rTMS sessions. The motor scale of upper extremity FMA (UE-FMA) and shoulder component of the UE-FMA were significantly improved in both low- and high-frequency rTMS groups. However, no significant improvement was observed in the wrist and hand components. No significant differences were noted in low- and high-frequency rTMS groups. The amplitude of motor evoked potential on the unaffected hemisphere showed a significant decrease in the low- and high-frequency stimulation groups. rTMS may be helpful in improving upper extremity motor function even in post-stroke patients with severe upper-limb motor impairment.
