Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends
10.1007/s13534-019-00115-x
- Author:
Namgue HONG
1
Author Information
1. Department of Pre-medical Science, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea. hnk210@dankook.ac.kr
- Publication Type:Review
- Keywords:
Photobiomodulation;
Neurodegenerative diseases;
Alzheimer's diseases;
Parkinson's diseases;
Epilepsy
- MeSH:
Alzheimer Disease;
Animal Experimentation;
Clinical Protocols;
Epilepsy;
Neurodegenerative Diseases;
Neurons;
Neuroprotection;
Parkinson Disease
- From:
Biomedical Engineering Letters
2019;9(3):359-366
- CountryRepublic of Korea
- Language:English
-
Abstract:
Photobiomodulation (PBM) is a rapidly growing as an innovative therapeutic modality for various types of diseases in recent years. Neuronal degeneration is irreversible process and it is proven to be difficult to slow down or stop the progression. Pharmacologic approaches to slow neuronal degeneration have been studied, but are limited due to concerns about the side effects. Therefore, it is necessary to develop a new therapeutic approach to stabilize neuronal degeneration and achieve neuronal protection against several neurodegenerative diseases. In this review, we have introduced several previous studies showing the positive effect of PBM over neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease and different types of epilepsy. Despite excellent outcomes of animal researches, not many clinical studies are conducted or showed positive outcome of PBM against neurodegenerative disease. To achieve clinical application of PBM against neurodegenerative disorder, determination of exact mechanism and establishment of effective clinical protocol seems to be necessary.
