Variability of electrochemical skin conductance for screening diabetes mellitus
10.1007/s13534-019-00111-1
- Author:
Soochan KIM
1
;
Junghee CHO
;
Boncho KU
;
Minho JUN
;
Gahye KIM
;
Horyong YOO
;
Sangsoo PARK
;
Jaeuk U KIM
Author Information
1. Department of Electrical, Electronics and Control Engineering and Research Center for Applied Human Sciences, Hankyong National University, Anseong, South Korea.
- Publication Type:Original Article
- Keywords:
Electrochemical skin conductance (ESC);
Diabetes;
Noninvasive diagnosis;
Oral glucose tolerance test
- MeSH:
Area Under Curve;
Blood Glucose;
Body Mass Index;
Diabetes Mellitus;
Glucose;
Glucose Tolerance Test;
Humans;
Mass Screening;
Meals;
Methods;
ROC Curve;
Skin
- From:
Biomedical Engineering Letters
2019;9(2):267-274
- CountryRepublic of Korea
- Language:English
-
Abstract:
Electrochemical skin conductance (ESC) has been suggested as a noninvasive diabetic screening tool. We examined the relevance of ESC method for screening type 2 diabetes. A meal tolerance test (MTT) was conducted for 40 diabetic and 42 control subjects stratifi ed by age, sex and body mass index (BMI). The glucose levels and ESC were measured before the MTT and every 30 min after meal intake up to 120 min. There was no correlation between the blood glucose level and ESC (r = 0.249) or ESC variability (ESCV) (r = −0.173). ESC (ESCV) was higher (lower) in diabetic patients than in normal control (p = 0.02 for ESC and p = 0.06 for ESCV). Receiver operating characteristic analysis showed that the area under the curve (AUC) values of the ESC and ESCV were 0.654 and 0.691, respectively. The novel variable, ESCV, showed 5.7% higher AUC than ESC. Contrary to some previous reports, ESC values in diabetic patients was higher than in age, sex and BMI matched control group. In our study, ESC or ESCV showed a marginal accuracy to be used as a screening tool for diabetes mellitus.
