A 5-year retrospective review of children with peanut allergy in the largest paediatric hospital in Singapore
10.5415/apallergy.2020.10.e6
- Author:
May Ping LEE
1
;
Seyed Ehsan SAFFARI
;
Wenyin LOH
;
Si Hui GOH
;
Anne GOH
;
Wen Chin CHIANG
;
Kok Wee CHONG
Author Information
1. Allergy Service, Department of Paediatric Medicine, KK Women's and Children's Hospital, Singapore. samantha.lee.mp@singhealth.com.sg
- Publication Type:Original Article
- Keywords:
Peanut allergy;
Children;
Singapore;
Asia
- MeSH:
Anacardium;
Anaphylaxis;
Arachis;
Asia;
Asthma;
Child;
Cohort Studies;
Diagnosis;
Eczema;
Humans;
Nuts;
Peanut Hypersensitivity;
Prevalence;
Prospective Studies;
Retrospective Studies;
Rhinitis, Allergic;
Risk Factors;
Singapore;
Skin;
Trees
- From:
Asia Pacific Allergy
2020;10(1):6-
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The prevalence of peanut allergy (PA) among children has increased significantly over the past decade. Even though the prevalence of PA in Singapore is considered low, peanut is the top trigger for food-induced anaphylaxis in Singaporean children.OBJECTIVE: To describe the demographic characteristics and clinical features of children with PA.METHODS: This is a 5-year retrospective review of children diagnosed with PA based on clinical history coupled with a positive skin prick test to peanut or positive oral food challenge results.RESULTS: There were 269 patients (53.9% males) with a clinical diagnosis of PA. The median age at first allergic presentation for the PA group was 24 months old, with interquartile range of 13–39 months. The most common form of peanut introduced was roasted peanut. The rate of peanut anaphylaxis was 7.1%. Concomitant tree nut sensitization was found in 32.3% of this cohort, predominantly to cashew nut. Majority of them have a personal history of atopy – 75.8% with eczema, 63.6% with allergic rhinitis, and 19.7% with asthma.CONCLUSION: This is the first large review of peanut-allergic children in Singapore. Prospective population-based studies are needed to establish the true prevalence and risk factors associated with the development of this potentially life-threatening condition.
