A case of acute motor axonal neuropathy associated with IgG GM1 antibody and Campylobacter Jejuni.
- Author:
Kyung Hoon HONG
1
;
Seung Hyun KIM
;
Young Bae LEE
;
Young Ju KEE
;
Hee Tea KIM
;
Ju Han KIM
;
Myung Ho KIM
Author Information
1. Dept of Neurology, College of Medicine, Hanyang University.
- Publication Type:Case Report
- MeSH:
Adult;
Autoantibodies;
Axons*;
Campylobacter jejuni*;
Campylobacter*;
Enteritis;
Enzyme-Linked Immunosorbent Assay;
Extremities;
Humans;
Immunoglobulin G*;
Male;
Polyneuropathies;
Reference Values
- From:Journal of the Korean Neurological Association
1997;15(5):1097-1101
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Guillain-Barre syndrom(GBS) is not a single entity, but may arise from a variety of pathogenic mechanisms. In GBS, abnormally increased autoantibody levels to GM, constitute a group with motor neuropathy predominantly and substantial axonal damage, particularly those following Campylobacter enteritis. We report a patient, 43 years old male, who presented with 3 days history of rapidly progressive weakness of all extremities. Electreophysiologic studies were suggestive of axonal form of motor dominant polyneuropathy, Using ELISA, autoantibody of MAG(myelin associated glycoprtein) and SGPG(sulfoglucuronyl paraglobiside) showed normal ranges, but IgG GM. Autoantibodies abnormally elevated. Additionally antibody titer of Campylobacter jejuni increased. We reported the axonal form of Guillain, Barr syndrome associated with IgG GM,, Ab and antiCampylobacter jejuni antibody.
