Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function
10.4168/aair.2020.12.2.364
- Author:
Eva E WALTL
1
;
Victoria STANEK
;
Christian A MUELLER
;
Renata KISS
;
Julia ECKL-DORNA
;
Rudolf VALENTA
;
Verena NIEDERBERGER
Author Information
1. Department of Otorhinolaryngology, Medical University of Vienna, Vienna, Austria. verena.niederberger@meduniwien.ac.at
- Publication Type:Brief Communication
- Keywords:
Respiratory epithelial barrier function;
allergic rhinitis;
allergen;
immunoglobulin E;
allergen-microarray;
transepithelial resistance
- MeSH:
Cytokines;
Epithelial Cells;
Humans;
Immunoglobulin E;
Rhinitis, Allergic
- From:Allergy, Asthma & Immunology Research
2020;12(2):364-370
- CountryRepublic of Korea
- Language:English
-
Abstract:
Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that primary nasal epithelial cells from allergic and non-allergic individuals showed comparable barrier function and secretion of cytokines.
