Endoscopic features aiding the diagnosis of gastric mucosa-associated lymphoid tissue lymphoma
- Author:
Byung Sam PARK
1
;
Si Hyung LEE
Author Information
- Publication Type:Review
- Keywords: Diagnosis; Follow-up studies; Gastrointestinal endoscopy; Marginal zone B-cell lymphoma; Stomach neoplasms
- MeSH: Biopsy; Diagnosis; Diagnostic Tests, Routine; Early Diagnosis; Endoscopy; Endoscopy, Digestive System; Endoscopy, Gastrointestinal; Endosonography; Follow-Up Studies; Humans; Incidence; Lymphoid Tissue; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Mucous Membrane; Stomach Neoplasms
- From:Yeungnam University Journal of Medicine 2019;36(2):85-91
- CountryRepublic of Korea
- Language:English
- Abstract: The incidence of gastric mucosa-associated lymphoid tissue (MALT) lymphoma is increasing worldwide, but the diagnosis is difficult. Most patients are asymptomatic or complain of nonspecific gastrointestinal symptoms. As the endoscopic features of gastric MALT lymphoma are variable and nonspecific, the possibility of this condition may be overlooked during esophagogastroduodenoscopy, and it remain undiagnosed. Therefore, this condition needs to be considered when an abnormal mucosa is observed during this procedure. Biopsy performed during endoscopy is the primary diagnostic test, but false negative results are possible; large numbers of samples should be collected from both normal and abnormal mucosae. Endoscopic ultrasonography is useful to assess the depth of invasion and to predict the treatment response. After treatment, follow-up tests are required every 3 months until complete remission is achieved, and annually thereafter. Early diagnosis of gastric MALT lymphoma is difficult, and its diagnosis and follow-up require wide experience and competent endoscopic technique.
