Expression of BMP4, BMP6 following sinus elevation with DBBP in rabbit
- Author:
Hyun Suk LEE
1
;
Hyun A HEO
;
Sung Woon PYO
;
Won LEE
Author Information
1. Department of Oral & Maxillofacial Surgery, Graduate School of Clinic Dental Science, The Catholic University of Korea, Korea. cmfs21@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Sinus elevation;
BMP4;
BMP6;
Deproteinated Bovine Bone Powder (DBBP);
Absorbable Gelatin Sponge (AGS)
- MeSH:
Animals;
Bone Morphogenetic Proteins;
Bone Regeneration;
Chungcheongnam-do;
Gelatin Sponge, Absorbable;
Maxillary Sinus;
Osseointegration;
Osteogenesis;
Rabbits;
RNA;
Transplants
- From:Journal of the Korean Association of Maxillofacial Plastic and Reconstructive Surgeons
2007;29(6):467-473
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
0.05). 2. The expression of BMP6 increased at postoperative 1 and 3 days in both DBBP group and AGS group. In AGS group, it decreased at postoperative 5 days, increased again at postoperative 7 days, and decreased at postoperative 9 days. In DBBP group, it increased until postoperative 7 days and decreased at postoperative 9 days. Although the expression of BMP6 was higher in AGS group compared with DBBP group, it was not statistically significant (p>0.05). 3. There was no statistically significant difference in BMP expression in both groups during same period of time. It's probably because DBBP and AGS both functioned as a space retainer so that the BMP expression in blood clot seemed to be similar. 4. Thus, DBBP would not offer many benefits for early bone regeneration compared with AGS. The expression of BMP in early bone formation seems to be more influenced by physical carrier rather than the graft type.]]>
