A Case of Rapidly Progressive Primary Sclerosing Cholangitis Requiring Liver Transplantation.
10.4285/jkstn.2013.27.1.24
- Author:
Tae Seop LIM
1
;
Jun Yong PARK
;
Soon Il KIM
;
Huapyong KANG
;
Moon Jae CHUNG
Author Information
1. Department of Internal Medicine, Yonsei Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. mjchung@yuhs.ac
- Publication Type:Case Report
- Keywords:
Primary sclerosing cholangitis;
Liver transplantation;
Ursodeoxycholic acid;
Endoscopic retrograde cholangiopancreatography;
Magnetic resonance cholangiopancreatography
- MeSH:
Abdominal Pain;
Bilirubin;
Cholangiopancreatography, Endoscopic Retrograde;
Cholangiopancreatography, Magnetic Resonance;
Cholangitis, Sclerosing;
Female;
Humans;
Liver;
Liver Diseases;
Liver Transplantation;
Reference Values;
Ursodeoxycholic Acid
- From:The Journal of the Korean Society for Transplantation
2013;27(1):24-28
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary sclerosing cholangitis (PSC) is a slowly progressive cholestatic liver disease. In cases of PSC, liver transplantation is the only effective treatment that can delay the disease's natural course. We report a case of rapidly progressive PSC requiring liver transplantation. A 52-year-old woman visited our hospital with abdominal pain. There was no evidence of PSC, as there was no elevation in cholestatic liver enzymes at her first visit. Although her total bilirubin was in a normal range at the initial visit, liver dysfunction progressed rapidly. Despite endoscopic procedures and ursodeoxycholic acid intake, total bilirubin levels rose to 18.9 mg/dL, and liver transplantation was performed 17 months after her first visit. PSC was pathologically confirmed after liver transplantation.
