A Case of Rheumatoid Arthritis Associated with Klinefelter's Syndrome.
- Author:
Mi Ryoung SEO
1
;
Hyun Jung CHO
;
Hyo Jin CHOI
;
Han Joo BAEK
;
Jeong Yeal AHN
Author Information
1. Department of Internal Medicine, Division of Rheumatology, Gil Medical Center, Gachon University of Medicine and Science, Incheon, Korea. hjchoi@gachon.ac.kr
- Publication Type:Case Report
- Keywords:
Klinefelter's syndrome;
Rheumatoid arthritis;
Sex hormones
- MeSH:
Adult;
Arthritis, Rheumatoid;
Gonadal Steroid Hormones;
Humans;
Hypogonadism;
Klinefelter Syndrome;
Male;
Sex Differentiation
- From:Korean Journal of Medicine
2011;81(3):412-415
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Klinefelter's syndrome is a disorder of sexual differentiation in males, characterized by the presence of two or more X-chromosomes, hypogonadism, and lack of secondary sexual characteristics. The association between Klinefelter's syndrome and systemic lupus erythematous has been described, while cases of rheumatoid arthritis associated with Klinefelter's syndrome are rare. We report the first Korean case: a 29-year-old man with Klinefelter's syndrome who developed rheumatoid arthritis. The sex hormone imbalance might have influenced the onset and course of his disease.
