Endoscopic Findings and Clinical Significance of Portal Hypertensive Colopathy.
10.4166/kjg.2011.58.6.332
- Author:
In Beom JEONG
1
;
Tae Hee LEE
;
Seong Min LIM
;
Ki Hyun RYU
;
Yong Seok KIM
;
Sun Moon KIM
;
Euyi Hyeog IM
;
Kyu Chan HUH
;
Young Woo CHOI
;
Young Woo KANG
Author Information
1. Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. green740@naver.com
- Publication Type:Original Article ; English Abstract
- Keywords:
Liver cirrhosis;
Portal hypertension;
Colopathy
- MeSH:
Adult;
Aged;
Colonoscopy;
Esophageal and Gastric Varices/etiology;
Female;
Humans;
Hypertension, Portal/complications/*pathology;
Intestinal Mucosa/pathology;
Irritable Bowel Syndrome/complications/*pathology;
Liver Cirrhosis/complications/*pathology;
Male;
Middle Aged;
Platelet Count;
Retrospective Studies;
Severity of Illness Index;
Thrombocytopenia/etiology
- From:The Korean Journal of Gastroenterology
2011;58(6):332-337
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: The endoscopic findings and clinical relevance of portal hypertensive colopathy are not well described in Korea. We aimed to do a retrospective study of mucosal changes in the colon of patients with liver cirrhosis and to find their association with clinical characteristics. METHODS: We reviewed the clinical data and endoscopic findings of 48 patients with liver cirrhosis and 48 patients, matched for age and sex, with irritable bowel disease (IBS) who underwent colonoscopy over a 5 year span. RESULTS: Patients with liver cirrhosis were more likely to have colitis-like lesions and vascular abnormalities than IBS patients. Low platelet count (p=0.005) and severe esophageal varices (p=0.011) were associated with portal hypertensive colopathy, whereas the etiologies and severity of cirrhosis were not associated with these findings. CONCLUSIONS: Portal hypertensive colopathy can be defined with colitis-like lesions or vascular lesions. These lesions are more frequently present in patients with more severe esophageal varices and thrombocytopenia.
