Nelson's Syndrome: A Case Report.
- Author:
Yang KWON
1
;
Hee Won JUNG
;
Je G CHI
;
Kil Soo CHOI
Author Information
1. Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Nelson's syndromey;
Adrenalectomy;
Cushing' syndrome;
Serum ACTH level;
Transsphenoidal surgery
- MeSH:
Adrenalectomy;
Adrenocorticotropic Hormone;
Cushing Syndrome;
Female;
Headache;
Hematoma;
Humans;
Hydrocortisone;
Hyperpigmentation;
Mucous Membrane;
Skin;
Young Adult
- From:Journal of Korean Neurosurgical Society
1987;16(4):1221-1226
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A case of Nelson's syndrome in 23 year-old female, developing 6 years after bilateral adrenalectomy for Cushing's syndrome, is reported. Presenting symptoms were headache and hyperpigmentation of the skin and mucous membrane. Serum ACTH level was markedly elebated above 1000 pg/ml, but serum cortisol level diminished markedly. Transsphenoidal approach (TSA) with removal of gushing out hematoma and tumor underwent. Postoperatively, headache subsided and hyperpigmentation of the skin markedly improved.
