Macular Pigment Optical Density in the Korean Population: a Cross Sectional Study
- Author:
In Hwan HONG
1
;
Woo Hyun JUNG
;
Jae Hyup LEE
;
In Boem CHANG
Author Information
- Publication Type:Original Article
- Keywords: Macular Pigment Optical Density; Dry Age-Related Macular Degeneration; Heterochromatic Flicker Photometry
- MeSH: Aging; Dyslipidemias; Healthy Volunteers; Humans; Hypertension; Linear Models; Logistic Models; Macular Degeneration; Macular Pigment; Mass Screening; Methods; Photometry; Retrospective Studies; Risk Factors; Smoke; Smoking
- From:Journal of Korean Medical Science 2020;35(5):30-
- CountryRepublic of Korea
- Language:English
- Abstract: 50 years) showed lower MPOD than younger (30–49 years) subjects. But, in the healthy population, the estimated MPOD values exhibited a decreasing trend with age, but there were no significant differences according to age, after excluding patients with AMD. MPOD was significantly lower in patients with AMD than in aged healthy controls. Furthermore, hypertension, dyslipidemia, and smoking were identified as risk factors for AMD.CONCLUSION: MPOD measured with MPSII® reflects the MP density in healthy individuals and patients with dry AMD. Aging was not significantly associated with low MPOD in healthy population, but the presence of dry AMD was significantly associated with low MPOD. Then, low MPOD may be a risk factor for development of dry AMD. Furthermore, routine screening with MPS II® for ages 50 and older is thought to help detect early low MPOD and identify individuals who should take supplements.]]>
