Histone deacetylase: a potential target for the treatment of atrial fibrillation
- VernacularTitle:组蛋白去乙酰化酶：心房颤动治疗的潜在靶点
- Author:
QIN Xiaoli
1
;
ZHANG Tailong
1
;
WU Zhong
1
Author Information
1. Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
- Publication Type:Journal Article
- Keywords:
Histone deacetylase;
atrial fibrillation;
atrial remodeling
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(02):214-217
- CountryChina
- Language:Chinese
-
Abstract:
Atrial fibrillation is a common arrhythmia associated with high mortality and morbidity, and the current treatment of atrial fibrillation is still limited. Histone deacetylase (HDAC) plays an important role in the pathophysiology of cardiovascular disease and promotes the occurrence of atrial fibrillation. Inhibition of HDAC may be a new therapeutic strategy through the regulation of atrial remodeling. Therefore, we reviewed the research progress of the HDAC and atrial fibrillation.
