Efficacy of Dairy Free Diet and 6-Food Elimination Diet as Initial Therapy for Pediatric Eosinophilic Esophagitis: A Retrospective Single-Center Study
10.5223/pghn.2020.23.1.79
- Author:
Jonathan WONG
1
;
Sue GOODINE
;
Kate SAMELA
;
Katherine S VANCE
;
Beth CHATFIELD
;
Zhu WANG
;
Wael N SAYEJ
Author Information
1. Department of Pediatrics, University of Connecticut School of Medicine, Farmington, CT, USA. wsayej@connecticutchildrens.org
- Publication Type:Original Article
- Keywords:
Eosinophilic esophagitis;
Restriction diet therapy;
Proton pump inhibitors
- MeSH:
Child;
Connecticut;
Diet;
Endoscopy;
Eosinophilic Esophagitis;
Eosinophils;
Humans;
Male;
Proton Pump Inhibitors;
Proton Pumps;
Retrospective Studies
- From:Pediatric Gastroenterology, Hepatology & Nutrition
2020;23(1):79-88
- CountryRepublic of Korea
- Language:English
-
Abstract:
12 weeks) were 81.8%, 50.0%, and 55.1% for DFD, and 68.8%, 50.0%, and 40.0% for SFED. Response based on age ( < 6, 6–12, and >12 years) were 59.3%, 42.9%, and 67.5% for DFD, and 36.4%, 58.8%, and 72.7% for SFED. In patients treated with DFD, concomitant proton pump inhibitor (PPI) administration resulted in improved outcomes (p=0.0177). Bivariate regression analysis showed that PPI with diet is the only predictor of response (p=0.0491), however, there were no significant predictors on multiple regression analysis.CONCLUSION: DFD and SFED are effective first line therapies for EoE. DFD should be tried first before extensive elimination diets. Concomitant therapy with PPI's may be helpful.]]>
