Ten Patients with General Fatigue Associated with Blood Stagnation Successfully Treated with Kampo Formulae, Keishibukuryogan and/or Tokakujokito
- VernacularTitle:桂枝茯苓丸，桃核承気湯の駆瘀血剤の一方または併用で疲労倦怠感が改善した10症例
- Author:
Yoko KIMURA
1
;
Mayuko YAMAZAKI
1
;
Hiroshi SATO
2
;
Takashi ITO
1
Author Information
- Keywords: blood stagnation; keishibukuryogan; tokakujokito; drugs for blood stagnation; general fatigue
- From:Kampo Medicine 2019;70(2):106-112
- CountryJapan
- Language:Japanese
- Abstract: In Kampo medicine, general fatigue is categorized as a symptom caused by qi deficiency according to the qi-blood-water criteria. However, in some patients with general fatigue, formulae for qi deficiency are not effective, and this might be because their chronic symptoms are associated with blood stagnation. Recently, we encountered ten patients (M/F 1/9, mean age 46 years, range 23-55 years) with general fatigue that was improved by agents for treating blood stagnation, such as keishibukuryogan and/or tokakujokito. These patients, who were mostly of medium build, complained of neck or shoulder stiffness (9/10), constipation (5/10), and blushing or hot flushes (5/10). They had no problem with appetite, except that 5 patients tended to overeat. Remarkable sublingual collateral vessels (8/10), paraumbilical tenderness (9/10) and periorbital dark circles (5/10) were observed on physical examination. The tongue and abdominal signs improved or had disappeared after treatment for 3 to 8 months. Our results suggest that patients with general fatigue, but who present with symptoms associated with blood stagnation, could be treated with drugs for blood stagnation such as keishibukuryogan and/or tokakujokito.
