Serological Survey of Zika Virus in Humans and Animals in Dejiang Prefecture, Guizhou Province, China.

Fan LI; Jing Zhu Zhou; Lei Zhou; Shi Hong FU; Zhen Zao Tian; Qi Wang; Nan Shao; Dan LI; Ying HE; Wen Wen Lei; Guang Peng Tang; Guo Dong Liang; Ding Ming Wang; Yan Ping Zhang; Huan Yu Wang

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Serological Survey of Zika Virus in Humans and Animals in Dejiang Prefecture, Guizhou Province, China.

Author: Fan LI ^{1
,

2} ; Jing Zhu ZHOU ³ ; Lei ZHOU ⁴ ; Shi Hong FU ^{1
,

2} ; Zhen Zao TIAN ³ ; Qi WANG ⁴ ; Nan SHAO ^{1
,

2} ; Dan LI ⁴ ; Ying HE ^{1
,

2} ; Wen Wen LEI ^{1
,

2} ; Guang Peng TANG ³ ; Guo Dong LIANG ^{1
,

2} ; Ding Ming WANG ³ ; Yan Ping ZHANG ⁴ ; Huan Yu WANG ^{1
,

2}
Author Information

1. NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
2. State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
3. Guizhou Center for Disease Control and Prevention, Guiyang 550004, China.
4. Public Health Emergency Center, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Publication Type:Journal Article
Keywords: Animals; China; Humans; Plague reduction neutralization test; Serological survey; Zika Virus
From: Biomedical and Environmental Sciences 2019;32(12):875-880
CountryChina
Language:English
Abstract: OBJECTIVE:The current outbreak of Zika virus (ZIKV) poses a severe threat to human health. Two ZIKV strains were isolated from mosquitoes collected from the Dejiang prefecture in China in 2016, which was the first isolation of ZIKV in nature in China.
METHODS:In this study, serum samples were collected from 366 healthy individuals and 104 animals from Dejiang prefecture in 2017, and the plaque reduction neutralization test (PRNT) was used to evaluate the seroprevalence of ZIKV.
RESULTS:None of the 366 residents from whom the samples were collected were seropositive for ZIKV. None of the 11 pigs from whom the samples were collected were seropositive for ZIKV, while 1 of 63 (1.59%) chickens and 2 of 30 (6.67%) sheep were seropositive for ZIKV.
CONCLUSION:The extremely low seropositivity rate of ZIKV antibodies in animals in the Dejiang prefecture, Guizhou province in this study indicates that ZIKV can infect animals; however, there is a low risk of ZIKV circulating in the local population.