Validity and Reliability of the Wristband Activity Monitor in Free-living Children Aged 10-17 Years.

Mohammad Mehdi Amin; Maryam Tabatabaeian; Afsane Chavoshani; Elham Amjadi; Majid Hashemi; Karim Ebrahimpour; Roya Klishadi; Sedigheh Khazaei; Marjan Mansourian

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Validity and Reliability of the Wristband Activity Monitor in Free-living Children Aged 10-17 Years.

Author: Mohammad Mehdi AMIN ^{1
,

2} ; Maryam TABATABAEIAN ³ ; Afsane CHAVOSHANI ^{4
,

5} ; Elham AMJADI ⁶ ; Majid HASHEMI ^{7
,

8} ; Karim EBRAHIMPOUR ^{1
,

2} ; Roya KLISHADI ⁹ ; Sedigheh KHAZAEI ¹⁰ ; Marjan MANSOURIAN ¹¹
Author Information

1. Environment Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
2. Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
3. Breast Surgeon, Board certificate in general surgery in Anahid Clinic, Isfahan, Iran.
4. Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran
5. Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran.
6. Anatomical Clinical Pathologist, Poursina Hakim Digestive Diseases Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
7. Environmental Health Engineering, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
8. Environmental Health Engineering Research Center, Kerman University of Medical Sciences, Kerman, Iran.
9. Child Growth and Development Research Center,Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
10. Microbiologist, Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
11. Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.
Publication Type:Journal Article
Keywords: Breast cancer; Demography; Malignant tissues; Normal tissues; Paraben; Risk factors
From: Biomedical and Environmental Sciences 2019;32(12):893-904
CountryChina
Language:English
Abstract: OBJECTIVE:Accumulation of estrogenic compounds and other carcinogens in normal breast tissues contributes to unpredictable breast cancer incidence during adolescence and throughout life. To assess the role of parabens in this phenomenon, the paraben content of adjacent normal-malignant breast tissues is measured in women with breast cancer living in Isfahan Province, Iran.
METHODS:Adjacent normal-malignant breast tissue samples were obtained from 53 subjects. The parabens including methyl-paraben (MePB), ethyl-paraben (EtPB), propyl-paraben (PrPB), and butylparaben (BuPB) were extracted from the sample supernatant and then subjected to gas chromatography analysis.
RESULTS:Some risk factors for breast cancer were stimulated by parabens in adjacent malignant-normal breast tissues among young and middle-aged women with breast cancer. We observed a significant association for dose-response pattern of MePB [OR = 98.34 (11.43-185.2), P = 0.027] for both ER+ and PR+ women and MePB [OR = 164.3 (CI: 112.3-216.3), P < 0.001] for HER2+ women than women with negative receptors. The risk of 95-fold increase in MePB dose and 164-fold increase in ΣPBs dose were significant for women with hereditary breast cancer in first-degree relatives.
CONCLUSION:These results may promote future epidemiology studies and strategies to improve women's lifestyle and consume paraben-free products.