Association between Metabolic Syndrome and Carotid Atherosclerosis: A Cross-sectional Study in Northern China.
- Author:
Ping An ZHOU
1
;
Chen Huan ZHANG
2
;
Yan Ru CHEN
3
;
Dong LI
3
;
Dai Yu SONG
3
;
Hua Min LIU
3
;
Ming Yue ZHOU
4
;
Guo Shun SONG
5
;
Sheng Yun CHEN
6
,
7
Author Information
- Publication Type:Journal Article
- Keywords: Carotid atherosclerosis; Components; Intima-media thickness; Metabolic syndrome
- From: Biomedical and Environmental Sciences 2019;32(12):914-921
- CountryChina
- Language:English
-
Abstract:
OBJECTIVE:Increased carotid artery intima-media thickness (CIMT) and carotid plaque as manifestations of carotid atherosclerosis have been used as markers of cardiovascular disease (CVD). The components of metabolic syndrome (MetS) are linked to CVD, but the association between MetS and CVD is controversial.
METHODS:A total of 8,933 Chinese adults aged 40 years or older from 2010 to 2014 were selected from the Jidong and Kailuan communities. MetS was defined by the International Diabetes Federation criteria. CIMT and carotid plaque were measured using color Doppler ultrasound. Logistic regression models were used to assess the association of MetS with carotid plaque and CIMT.
RESULTS:MetS was found among 3,461 (3,461/8,933) participants. The odds ratio and 95% confidence internal (CI) for carotid plaques in participants with MetS was 1.16 (1.03-1.30). The risk of carotid plaques increased with the number of MetS components. The average CIMT was higher in participants with MetS (β = 0.020, 95% CI, 0.014-0.027) and in participants with more MetS components.
CONCLUSION:Individuals with MetS are at an increased risk for carotid atherosclerosis compared to those without MetS.
