Analysis of Preoperative Factors Influencing Hypoglossal-facial 'Side'-to-side Neurorrhaphy for Facial Paralysis after Excision of Acoustic Neuroma.

Di Ya SU; Hong Wan; De Zhi LI; Hui Qiao; Michael Schumacher; Song Liu

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Analysis of Preoperative Factors Influencing Hypoglossal-facial 'Side'-to-side Neurorrhaphy for Facial Paralysis after Excision of Acoustic Neuroma.

Author: Di Ya SU ^{1
,

2} ; Hong WAN ³ ; De Zhi LI ⁴ ; Hui QIAO ³ ; Michael SCHUMACHER ⁵ ; Song LIU ^{1
,

5
,

6}
Author Information

1. Beijing Neurosurgical Institute and Beijing Key Laboratory of Central Nervous System Injury, Capital Medical University, Beijing 100070, China
2. Dalian University Affiliated Xinhua Hospital, Dalian 116000, Liaoning, China.
3. Beijing Neurosurgical Institute and Beijing Key Laboratory of Central Nervous System Injury, Capital Medical University, Beijing 100070, China.
4. Department of Neurosurgery and China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
5. U 1195, INSERM and University Paris-Sud and University Paris Saclay, 94276 Le Kremlin-Bicêtre, France.
6. Department of Neurosurgery and China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China
Publication Type:Journal Article
Keywords: Facial nerve injury; Nerve regeneration; Preoperative factors analysis
From: Biomedical and Environmental Sciences 2020;33(1):30-36
CountryChina
Language:English
Abstract: Objective:Hypoglossal nerve-facial nerve 'side'-to-side neurorrhaphy is a new method for the treatment of potential incomplete facial paralysis after acoustic neuroma. However, there are differences in postoperative outcomes among patients. This study analysed preoperative factors that may influence the treatment outcomes of neurorrhaphy.
Methods:We performed a retrospective study of 53 patients who were treated by neurorrhaphy for facial paralysis after acoustic neuroma resection. After a one-year follow-up period, the patients were divided into two groups according to facial functional outcome: better recovery or ordinary recovery. We analysed the following factors: gender, age, tumour size, and characteristics, tumour adhesion to the facial nerve, the duration of facial paralysis (DFP) and F wave appearance prior to neurorrhaphy (F wave).
Results:Univariate analysis showed significant differences between the two groups in DFP ( = 0.0002), tumour adhesion to the facial nerve ( = 0.0079) and F waves ( = 0.0048). Logistic regression analysis of these factors also showed statistical significance with values of 0.042 for the DFP, 0.043 for F waves, and 0.031 for tumour adhesion to the facial nerve.
Conclusions:Tumour adhesion to the facial nerve, F waves appearance and DFP prior to neurorrhaphy are the predominant factors that influence treatment outcomes.