Relationship among areca nut, intracellular reactive oxygen species, and autophagy.

Author: Zhi XU ¹ ; Feng-Yuan LÜ ² ; Er-Hui JIANG ³ ; Xiao-Ping ZHAO ² ; Zheng-Jun SHANG ³
Author Information

1. Dept. of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
2. Center of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
3. The State Key Laboratory Breeding Base of Basic Science of Stomatology Hubei-MOST & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China.
Publication Type:Journal Article
Keywords: areca nut; autophagy; oral cavity cancer; oral submucous fibrosis; reactive oxygen species
MeSH: Areca; Autophagy; Humans; Mouth Neoplasms; Nuts; Oral Submucous Fibrosis; Reactive Oxygen Species
From: West China Journal of Stomatology 2020;38(1):80-85
CountryChina
Language:Chinese
Abstract: The relationship between areca nut as a primary carcinogen and oral cancer has been widely concerned. Areca can change the levels of reactive oxygen species (ROS) and autophagy in cells, and the levels of ROS and autophagy are closely related to the occurrence and development of tumors. This paper reviewed the relationships among areca nut, intracellular ROS, and autophagy.