Preoperative C-reactive protein level has a dose-response relationship with postoperative complications in elderly patients with femoral neck fracture.
10.12122/j.issn.1673-4254.2019.12.18
- Author:
Changsheng ZHAO
1
;
Junfeng WANG
1
;
Heng ZHANG
1
;
Xiaohua WANG
1
;
Bin SUN
1
;
Ke ZHANG
1
;
Bin YANG
1
Author Information
1. Department of Orthopedics, Peking University International Hospital, Beijing 102206, China.
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
femoral neck fracture;
postoperative complications
- MeSH:
Aged;
Aged, 80 and over;
C-Reactive Protein;
Female;
Femoral Neck Fractures;
Humans;
Male;
Postoperative Complications;
Retrospective Studies
- From:
Journal of Southern Medical University
2019;39(12):1511-1514
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the association of preoperative C-reactive protein (CRP) level with postoperative complications in elderly patients undergoing surgeries for femoral neck fracture.
METHODS:We retrospectively analyzed the data of 147 elderly patients (median age 80 years; 73.5% of the patients were female) undergoing surgeries for femoral neck fracture. According to preoperative CRP level, the patients were divided into normal CRP (< 10 mg/L) group (31 patients), mild elevation group (CRP level of 10-40 mg/L; 51 patients), and severe elevation group (CRP ≥40 mg/L; 65 patients). The association of preoperative CRP levels with postoperative complications was analyzed.
RESULTS:Preoperative CRP level was significantly correlated with the occurrence of postoperative complications (=0.003). Compared with that in normal CRP group, the unadjusted ORs in mild and severe elevation groups were 0.97 (95%: 0.29-3.27) and 3.04 (95%: 1.03-8.98) with the adjusted ORs of 1.13 (95%: 0.33-3.90) and 4.89 (95%: 1.47-16.26), respectively.
CONCLUSIONS:Preoperative CRP level has a dose-response relationship with complications in elderly patients following arthroplasty for femoral neck fracture, and the patients with a preoperative CRP level ≥40 mg/L are exposed to a significantly increased risk for postoperative complications by 3.89 folds compared with the patients with a normal CRP level.
