Predictive value of inflammation-based Glasgow prognostic score for the prognosis in patients with ST-segment elevation myocardial infarction
- VernacularTitle:基于炎症的格拉斯哥预后评分对急性 ST 段抬高型心肌梗死患者预后的预测价值分析
- Author:
YUAN Jianying
1
,
2
;
CHENG Yisong
1
,
2
,
3
;
JIA Yu
1
,
2
;
LI Dongze
1
,
2
;
LIU Hong
4
;
LI Fanghui
4
;
ZENG Rui
4
;
LIAO Xiaoyang
5
;
WAN Zhi
1
,
2
;
CAO Yu
1
,
2
;
ZENG Zhi
4
Author Information
1. 1. Department of Emergency Medicine, Emergency Medical Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
2. 2. Disaster Medical Center, Sichuan University, Chengdu, 610041, P.R.China
3. 4. Department of Cardiology, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
4. Department of Cardiology, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
5. Department of General Practice, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
- Publication Type:Journal Article
- Keywords:
Glasgow prognostic score;
ST-segment elevation myocardial infarction;
prognosis prediction
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2020;27(01):14-19
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze prognostic ability of inflammation-based Glasgow prognostic score (GPS) in patients with ST-segment elevation myocardial infarction (STEMI). Methods We retrospectively analyzed the clinical data of 289 patients with STEMI admitted to the Department of Emergency in West China Hospital from April 2015 to January 2016. All study subjects were divided into three groups: a group of GPS 0 (190 patients including 150 males and 40 females aged 62.63±12.98 years), a group of GPS 1 (78 patients including 58 males and 20 females aged 66.57±15.25 years), and a group of GPS 2 (21 patients including 16 males and 5 females aged 70.95±9.58 years). Cox regression analysis was conducted to analyze the independent risk factors of predicting long-term mortality of patients with STEMI. Results There was a statistical difference in long-term mortality (9.5% vs. 23.1% vs. 61.9%, P<0.001) and in-hospital mortality (3.7% vs. 7.7% vs. 23.8%, P<0.001) among the three groups. The Global Registry of Acute Coronary Events (GRACE) scores and Gensini scores increased in patients with higher GPS scores, and the differences were statistically different (P<0.001). Multivariable Cox regression analysis showed that the GPS was independently associated with STEMI long-term all-cause mortality (1 vs. 0, HR: 2.212, P=0.037; 2 vs. 0, HR: 8.286, P<0.001). Conclusion GPS score is helpful in predicting the long-term and in-hospital prognosis of STEMI patients, and thus may guide clinical precise intervention by early risk stratification.
