Refractory Clostridium difficile Infection Cured With Fecal Microbiota Transplantation in Vancomycin-Resistant Enterococcus Colonized Patient.
- Author:
Mi Ok JANG
1
;
Jun Hwan AN
;
Sook In JUNG
;
Kyung Hwa PARK
Author Information
- Publication Type:Case Report
- Keywords: Clostridium difficile; Fecal microbiota transplantation; Vancomycin-resistant Enterococcus; Enterocolitis, pseudomembranous; Fecal bacteriotherapy
- MeSH: Clostridium difficile*; Colon*; Enterococcus*; Enterocolitis, Pseudomembranous; Humans; Microbiota*
- From:Intestinal Research 2015;13(1):80-84
- CountryRepublic of Korea
- Language:English
- Abstract: The rates and severity of Clostridium difficile infections, including pseudomembranous colitis, have increased markedly. However, there are few effective treatments for refractory or recurrent C. difficile infections and the outcomes are poor. Fecal microbiota transplantation is becoming increasingly accepted as an effective and safe intervention in patients with recurrent disease, likely due to the restoration of a disrupted microbiome. Cure rates of >90% are being consistently reported from multiple centers. We cured a case of severe refractory C. difficile infection with fecal microbiota transplantation in a patient colonized by vancomycin-resistant enterococcus.
