Prevalence of HIV, Hepatitis B and C Virus Co-infections among Iranian High-Risk Groups: A Systematic Review and Meta- Analysis

Amir Almasi Hashiani; Farzin Sadeghi; Erfan Ayubi; Shahab Rezaeian; Yousef Moradi; Kamyar Mansori; Behzad Gholamaliei; Abolfazl Mohammadbeigi; Salman Khazaei

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Prevalence of HIV, Hepatitis B and C Virus Co-infections among Iranian High-Risk Groups: A Systematic Review and Meta- Analysis

Author: Amir Almasi Hashiani ¹ ; Farzin Sadeghi ^{2
,

3} ; Erfan Ayubi ⁴ ; Shahab Rezaeian ⁵ ; Yousef Moradi ⁶ ; Kamyar Mansori ⁷ ; Behzad Gholamaliei ⁸ ; Abolfazl Mohammadbeigi ⁹ ; Salman Khazaei ¹⁰
Author Information

1. Department of Epidemiology, Arak University of Medical Sciences, Arak, Iran and Traditional and Complementary Medicine Research Center, Arak University of Medical Sciences, Arak, Iran
2. Infectious Diseases &
3. Tropical Medicine Research Center, Babol University of Medical Sciences, Babol, Iran
4. Department of Community Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
5. Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran
6. Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran
7. Department of Epidemiology and Biostatistics, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
8. Department of Public Health, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
9. Research Center of Gastroenterology and Hepatology, Qom University of Medical Sciences, Qom, Iran
10. Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran
Publication Type:Journal Article
Keywords: Keywords; HIV infection, hepatitis B, hepatitis C, co-infection
From:Malaysian Journal of Medical Sciences 2019;26(3):37-48
CountryMalaysia
Language:English
Abstract: Co-infection with hepatitis B and C among HIV infected patients are prevalent among high-risk populations. This meta-analysis aimed to estimate the prevalence of HIV, HCV and HBV co-infections among high-risk populations in Iran. We systematically searched the national and international electronic databases until 2016. The primary outcome was the prevalence of HIV, HBV, HCV and HIV co-infections in different high-risk populations in Iran. All English and Persian studies conducted on Iranian high-risk groups were included in the study. The review was reported based on PRISMA guidelines and data were analysed at 95% confidence level using random effect models.Overall, 916 relevant papers were recognised and 14 articles were included in the metaanalysis. The pooled estimates of HBV/HCV, HCV/HIV, HBV/HIV and HBV/HCV/HIV were 1.3% (95%CI: 0.5–2.1), 16.3% (95%CI: 1.1–31.6), 0.5% (95%CI: 0–1.4) and 0.5% (95%CI: 0.2–0.8), respectively. Based on subgroup analysis, there was a higher proportion of all co-infections from the years 2010–2016 as compared to that of the years 2003–2009. Our results highlighted that HCV/HIV co-infection in Iranian high-risk groups including injection drug users (IDUs) and prisoners is common. In addition, the increasing trend of coinfections should be considered alarming for policymakers.
Full text:3.2019my0785.pdf