Prevalence of HIV, Hepatitis B and C Virus Co-infections among Iranian High-Risk Groups: A Systematic Review and Meta- Analysis
- Author:
Amir Almasi Hashiani
1
;
Farzin Sadeghi
2
,
3
;
Erfan Ayubi
4
;
Shahab Rezaeian
5
;
Yousef Moradi
6
;
Kamyar Mansori
7
;
Behzad Gholamaliei
8
;
Abolfazl Mohammadbeigi
9
;
Salman Khazaei
10
Author Information
- Publication Type:Journal Article
- Keywords: Keywords; HIV infection, hepatitis B, hepatitis C, co-infection
- From:Malaysian Journal of Medical Sciences 2019;26(3):37-48
- CountryMalaysia
- Language:English
- Abstract: Co-infection with hepatitis B and C among HIV infected patients are prevalent among high-risk populations. This meta-analysis aimed to estimate the prevalence of HIV, HCV and HBV co-infections among high-risk populations in Iran. We systematically searched the national and international electronic databases until 2016. The primary outcome was the prevalence of HIV, HBV, HCV and HIV co-infections in different high-risk populations in Iran. All English and Persian studies conducted on Iranian high-risk groups were included in the study. The review was reported based on PRISMA guidelines and data were analysed at 95% confidence level using random effect models.Overall, 916 relevant papers were recognised and 14 articles were included in the metaanalysis. The pooled estimates of HBV/HCV, HCV/HIV, HBV/HIV and HBV/HCV/HIV were 1.3% (95%CI: 0.5–2.1), 16.3% (95%CI: 1.1–31.6), 0.5% (95%CI: 0–1.4) and 0.5% (95%CI: 0.2–0.8), respectively. Based on subgroup analysis, there was a higher proportion of all co-infections from the years 2010–2016 as compared to that of the years 2003–2009. Our results highlighted that HCV/HIV co-infection in Iranian high-risk groups including injection drug users (IDUs) and prisoners is common. In addition, the increasing trend of coinfections should be considered alarming for policymakers.
- Full text:3.2019my0785.pdf