The Incidence of Thyroid Gland Invasion in Patients with Carcinoma of the Larynx who Underwent Total Laryngectomy
- Author:
Mawaddah A
- Collective Name: See-Sze S, Marina MB, Pua KC, Abdullah-Sani M
- Publication Type:Journal Article
- Keywords:
Thyroidectomy, Cancer of the Larynx, Laryngectomy.
- From:
The International Medical Journal Malaysia
2019;18(1):13-20
- CountryMalaysia
- Language:English
-
Abstract:
Introduction: Total thyroidectomy or at least hemithyroidectomy is routinely performed alongside total
laryngectomy in patients with advanced carcinoma of the larynx. Life-threatening hypocalcaemia and
hypothyroidism are common sequelae especially with adjuvant radiation. The study aims to determine the
incidence of microscopic thyroid gland invasion and challenge the idea of routine thyroidectomy in advanced
carcinoma of the larynx. Materials and Methods: This study was a retrospective observational study. It was
done in two tertiary centres in Malaysia between 2003 and 2013 for a total duration of 11 years. A total of 72
patients were included in this study. Data from medical records, operative notes, and histopathological
reports were collected and analysed. Results: Three patients (4.2%) had the presence of microscopic thyroid
gland invasion. There were no significant associations between microscopic thyroid gland invasion and
tumour subsites, histological types of a tumour nor T staging (p>0.05) Conclusion: The incidence of
microscopic thyroid gland invasion in advance carcinoma of the larynx is low, disavowing routine
thyroidectomy. Limitations: Some factors such as cartilage invasion on CT imaging and central lymph node
treatment were not considered due to limitations in case documentation.
- Full text:180119.pdf
